Bacillus Calmette-Guerin vaccine and bladder cancer incidence: Scoping literature review and preliminary analysis

Background: The Bacillus Calmette-Guerin (BCG) vaccine has long been used for the prevention of tuberculosis (TB) around world. BCG is also as an immunotherapy agent treatment non-muscle invasive urinary bladder cancer. This scoping literature review and preliminary data analysis aims to summarize correlating infantile vaccination with incidence future Methods: Studies were identified by a formal search MEDLINE Cochrane Central Registrar Controlled Trials following PRISMA guidelines. Preliminary was conducted on publicly accessible summarizing impact gender, vaccination, socio-economic effects crude age-standardized rates Results: As part our analysis, regression models demonstrated status, status have statistically significant cancer incidence. associated 35-37% lower rate Conclusions: There very little examining relationship between prior Our limited indicates that does exist later development, although extensive investigation needed in this area.